Publications

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Displaying 1 through 50 of 82 publications.

Fleming AD, Mellor J, McGurnaghan SJ, Blackbourn LAK, Goatman KA, Styles C, Storkey AJ, McKeigue PM, Colhoun HM. Deep learning detection of diabetic retinopathy in Scotland's diabetic eye screening programme. Br J Ophthalmol. 2024 Jun 20;108(7):984-8. doi: 10.1136/bjo-2023-323395

Krause T, Fleming A, Hurst M, Zema C, Costello J, Hawe E, Ling C. Prognostic factors and surrogate endpoints in obstructive hypertrophic cardiomyopathy: a systematic literature review. Poster presented at the ISPOR Europe 2023; November 14, 2023. Copenhagen, Denmark. [abstract] Value Health. 2023 Dec; 26(12 Supplement):S36. doi: 10.1016/j.jval.2023.09.189

Mellor J, Jiang W, Fleming A, McGurnaghan SJ, Blackbourn L, Styles C, Storkey AJ, McKeigue PM, Colhoun HM, Scottish Diabetes Research Network Epidemiology Group. Can deep learning on retinal images augment known risk factors for cardiovascular disease prediction in diabetes? a prospective cohort study from the national screening programme in Scotland. Int J Med Infrom. 2023 Jul;175:105072. doi: 10.1016/j.ijmedinf.2023.105072

Fleming AD, Mellor J, Jiang W, Storkey A, Styles CJ, McKeigue PM, Colhoun HM. Safe and efficient 2-year screening intervals allocated by manual and automated grading in nationwide diabetic retinopathy screening. Poster presented at the 58th EASD Annual Meeting; September 19, 2022. Stockholm, Sweden. [abstract] Diabetologia. 2022 Aug 3; 65(supplement 1):372. doi: 10.1007/s00125-022-05755-w

Mellor J, Jiang W, Fleming AD, Styles CJ, Storkey A, McKeigue PM, Colhoun HM, Scottish Diabetes Research Network. Evaluation of deep learning prediction models for cardiovascular risk prediction using fundus images from the Scottish Diabetic Retinopathy Screening programme. Poster presented at the 58th EASD Annual Meeting of the European Association for the Study of Diabetes; September 19, 2022. Stockholm, Sweden. [abstract] Diabetologia. 2022 Aug 3; 65(Supple 1):S408-9. doi: 10.1007/s00125-022-05755-w

Fan W, Uji A, Nittala M, Wykoff CC, Brown D, Fleming A, Robertson G, van Hemert J, Sadda S, Ip MS. Retinal vascular bed area on ultra-wide field fluorescein angiography indicates the severity of diabetic retinopathy. Br J Ophthalmol. 2022 Aug;106(8):1126-31. doi: 10.1136/bjophthalmol-2020-317488

Jacoba CMP, Ashraf M, Cavallerano JD, Tolson AM, Tolls D, Pellegrini E, Fleming A, Sun JK, Aiello LP, Silva PS. Association of maximizing visible retinal area by manual eyelid lifting with grading of diabetic retinopathy severity and detection of predominantly peripheral lesions when using ultra-widefield imaging. JAMA Ophthalmol. 2022 Apr 1;140(4):421-5. doi: 10.1001/jamaophthalmol.2021.6363

Fan W, Nittala MG, Wykoff CC, Brown DM, Uji A, Hemert JV, Fleming A, Robertson G, Sadda SR, Ip M. New biomarker quantifying the effect of anti-vegf therapy in eyes with proliferative diabetic retinopathy on ultra-wide field fluorescein angiography: recovery study. Retina - J Ret Vit Dis. 2022 Mar 1;42(3):426-33. doi: 10.1097/IAE.0000000000003358

Ashraf M, Shokrollahi S, Pisig AU, Sampani K, Abdelal O, Cavallerano JD, Robertson G, Fleming A, van Hemert J, Pitoc CM, Sun JK, Aiello LP, Silva PS. Retinal vascular caliber association with nonperfusion and diabetic retinopathy severity depends on vascular caliber measurement location. Ophthalmol Retina. 2021 Jun;5(6):571-9. doi: 10.1016/j.oret.2020.09.003

Ashraf M, Rageh A, Gilbert M, Tolls D, Fleming A, Souka A, El-Baha S, Cavallerano JD, Sun JK, Aiello LP, Silva PS. Factors affecting predominantly peripheral lesion identification and grading. Transl Vis Sce Techn. 2021 Jun 1;10(7):6. doi: 10.1167/tvst.10.7.6

Rageh A, Ashraf M, Fleming A, Silva PS. Automated microaneurysm counts on ultrawide field color and fluorescein angiography images. Semin Ophthalmol. 2021 May 19;36(4):315-21. doi: 10.1080/08820538.2021.1897852

Ashraf M, Sampani K, Abdelal O, Fleming A, Cavallerano J, Souka A, El Baha SM, Silva PS, Sun J, Aiello LP. Disparity of microaneurysm count between ultrawide field colour imaging and ultrawide field fluorescein angiography in eyes with diabetic retinopathy. Br J Ophthalmol. 2020 Dec;104(12):1762-7. doi: 10.1136/bjophthalmol-2019-315807

Fan W-Y, Fleming A, Robertson G, Uji A, van Hemert J, Singer M, Sagong M, Ip M, Sadda SR. Fractal analysis of retinal vasculature in normal subjects on ultra-wide field fluorescein angiography. Int J Ophtalmol. 2020 Jul 18;13(7):1109-14. doi: 10.18240/ijo.2020.07.15

Pellegrini E, Fleming A, Sinai M, London N, van Hemert J. Correlation of retinal thickness measures and optic nerve head parameters between different OCT scan types. Poster presented at the 2020 Association for Research in Vision & Ophthalmology Annual Meeting (ARVO); May 2020. Baltimore, MD. [abstract] Invest Ophth Vis Sci. 2020 Jul; 61(9):PB00102.

Elmasry MA, Sampani K, Abdelal OM, Fleming A, Souka A, Elbaha S, Silva PS, Sun JK, Aiello LP. Disparity of microaneurysm count between ultrawide field color imaging (UWF-CI) and ultrawide field fluorescein angiography (UWF-FA) in eyes with diabetic retinopathy. Poster presented at the ARVO Annual Meeting; May 3, 2020. Baltimore, MD. [abstract] Invest Ophth Vis Sci. 2020 Jun; 61(7):5306.

Silva PS, Cavallerano J, Elmasry MA, Fleming A, van Hemert J, Lewis D, Bhaskar V, Tolson A, Tolls D, Sun JK, Aiello LP. Impact of visible retinal area on diabetic retinopathy severity and detection of predominantly peripheral lesions when using ultrawide field imaging. Poster presented at the ARVO Annual Meeting; May 3, 2020. Baltimore, MD. [abstract] Invest Ophth Vis Sci. 2020 Jun 1; 61(7):3201.

Wakeford PR, Pellegrini E, Robertson G, Verhoek M, Fleming AD, van Hemert J, Heng IS. Optic disc and fovea localisation in ultra-widefield scanning laser ophthalmoscope images captured in multiple modalities. Poster presented at the MIUA 2019 Annual Conference; July 24, 2019. Liverpool, United Kingdom. [abstract] CCIS. 2020 Jan 24; 1065:399-410. doi: 10.1007/978-3-030-39343-4_34

Robertson G, Fleming A, Williams MC, Trucco E, Quinn N, Hogg R, McKay GJ, Kee F, Young I, Pellegrini E, Newby DE, van Beek EJR, Peto T, Dhillon B, van Hemert J, MacGillivray TJ. Association between hypertension and retinal vascular features in ultra-widefield fundus imaging. Open Heart. 2020 Jan 8;7(1):e001124. doi: 10.1136/openhrt-2019-001124

Fan W, Nittala MG, Fleming A, Robertson G, Uji A, Wykoff CC, Brown DM, van Hemert J, Ip M, Wang K, Falavarjani KG, Singer M, Sagong M, Sadda S. Relationship between retinal fractal dimension and nonperfusion in diabetic retinopathy on ultrawide-field fluorescein angiography. Am J Ophthalmol. 2020 Jan 1;209:99-106. doi: 10.1016/j.ajo.2019.08.015

Fan W, Nittala MG, Velaga SB, Hirano T, Wykoff CC, Ip M, Lampen SIR, van Hemert J, Fleming A, Verhoek M, Sadda SR. Distribution of nonperfusion and neovascularization on ultrawide-field fluorescein angiography in proliferative diabetic retinopathy (RECOVERY study): report 1. Am J Ophthalmol. 2019 Oct 1;206:154-60. doi: 10.1016/j.ajo.2019.04.023

Elmasry MA, Sampani K, Pitoc CM, Fleming A, Robertson G, Silva PS, Aiello LP, Sun JK. Differential association of macular superficial versus deep vascular density with microaneurysms and nonperfusion in diabetic retinopathy. Poster presented at the 2019 ARVO Annual Meeting; April 28, 2019. Vancouver, Canada. [abstract] Invest Ophth Vis Sci. 2019 Jul 1; 60(9):5344.

Pead E, Megaw R, Cameron J, Fleming A, Dhillon B, Trucco E, MacGillivray T. Automated detection of age-related macular degeneration in color fundus photography: a systematic review. Surv Ophthalmol. 2019 Jul 1;64(4):498-511. doi: 10.1016/j.survophthal.2019.02.003

Shokrollahi S, Elmasry MA, Sampani K, Pisig AU, Abdelal O, Robertson G, Fleming A, Pitoc CM, Sun JK, Silva PS, Aiello LP. Association of ultrawide field (UWF) retinal vessel caliber with diabetic retinopathy (DR) severity, predominantly peripheral lesions (PPL) and retinal nonperfusion (NP). Poster presented at the 2019 ARVO Annual Meeting; April 28, 2019. Vancouver, Canada. [abstract] Invest Ophth Vis Sci. 2019 Jul 1; 60(9):4771.

Silva PS, Stanton RC, Elmasry MA, Fleming A, Pellegrini E, van Hemert J, Tolls D, Tolson AM, Lewis D, Stainback J, Cavallerano JD, Sun JK, Aiello LP. Association of systemic comorbities with predominantly peripheral diabetic retinopathy lesions (PPL) identified on ultrawide field (UWF) retinal imaging. Poster presented at the 2019 ARVO Annual Meeting; April 28, 2019. Vancouver, Canada. [abstract] Invest Ophth Vis Sci. 2019 Jul 1; 60(9):4772.

Gupta A, El-Rami H, Barham R, Fleming A, van Hemert J, Sun JK, Silva PS, Aiello LP. Effect of phase-plate adjustment on retinal image sharpness and visible retinal area on ultrawide field imaging. Eye (Lond). 2019 Apr 1;33(4):587-91. doi: 10.1038/s41433-018-0270-5

Robertson G, Fleming A, Williams MC, Trucco E, Quinn N, Hogg RE, McKay GJ, Pellegrini E, Newby DE, van Beek EJ, Peto T, Dhillon B, van Hemert J, MacGillivray T. Screening for hypertension using retinal vascular calibre in ultra-widefield fundus imaging. Poster presented at the American Heart Association's Joint Hypertension 2018 Scientific Sessions; September 6, 2018. Chicago, IL. [abstract] Hypertension. 2018 Dec 6; 72:AP400. doi: 10.1161/hyp.72.suppl_1.P400

Robertson G, Peto T, van Beek E, Fleming A, van Hemert J, Williams MC, Trucco E, Quinn N, Hogg R, McKay G, Pellegrini E, Newby DE, Dillon B, Kee F, Young I, MacGillivray T. Classification of hypertension using nasal annular arteriole-venule ratio in ultra-widefield ophthalmic imaging. Poster presented at the Joint Hypertension 2018 Scientific Sessions; September 6, 2018. Chicago, United Kingdom.

Pisig AU, Sampani K, Elmasry MA, Aldairy Y, Robertson G, Fleming A, Pitoc C, Rhee J, Sun JK, Silva PS, Aiello LP. Regional vessel caliber, retinal oximetry and predominantly peripheral diabetic retinal lesions as surrogate markers of nonperfusion on ultrawide field angiography in diabetic eyes. Poster presented at the 2018 ARVO Annual Meeting; April 29, 2018. Honolulu, HI. [abstract] Invest Ophth Vis Sci. 2018 Jul 1; 59(9):3448.

Silva PS, Elmasry M, Pisig A, Aldairy Y, van Hemert J, Fleming A, Sun JK, Aiello LP. Automated hemorrhage and microaneurysm counts on ultrawide field images predict increased risk of diabetic retinopathy progression over 4 years. Poster presented at the 2018 ARVO Annual Meeting; April 29, 2018. Honolulu, HI. [abstract] Invest Ophth Vis Sci. 2018 Jul 1; 59(9):737.

Sears CM, Hirano T, Nittala MG, Mehta NS, Sinha S, Jayadev C, Singh G, Verhoek M, Fleming A, van Hmert J, Tsui I, Prasad P, Sadda SR. Ethnic variation in diabetic retinopathy lesion distribution. Poster presented at the 2018 ARVO Annual Meeting; April 29, 2018. Honolulu, HI. [abstract] Invest Ophth Vis Sci. 2018 Jul 1; 59(9):4681.

Sears CM, Nittala MG, Jayadev C, Verhoek M, Fleming A, van Hemert J, Tsui I, Sadda S. Comparison of subjective assessment and precise quantitative assessment of lesion distribution in diabetic retinopathy. JAMA Ophthalmol. 2018 Apr 1;136(4):365-71. doi: 10.1001/jamaophthalmol.2018.0070

Haleem MS, Han L, van Hemert J, Li B, Fleming A, Pasquale LR, Song BJ. A novel adaptive deformable model for automated optic disc and cup segmentation to aid glaucoma diagnosis,. J Med Syst. 2017 Dec 7;42(1):20. doi: 10.1007/s10916-017-0859-4

Silva PS, El-Rami H, Barham R, Gupta A, Fleming A, van Hemert J, Cavallerano JD, Sun JK, Aiello LP. Hemorrhage and/or microaneurysm severity and count in ultrawide field images and early treatment diabetic retinopathy study photography. Ophthalmology. 2017 Jul 1;124(7):970-6. doi: 10.1016/j.ophtha.2017.02.012.

Silva PS, Rami HE, Barham R, Gupta A, Fleming A, van Hemert J, Sun JK, Aiello LP. Hemorrhages and/or microaneurysm distribution and counts identified on ultrawide field imaging and the risk of diabetic retinopathy progression over 4 years. Poster presented at the 2017 ARVO Annual Meeting; May 7, 2017. Baltimore, MD. [abstract] Invest Ophth Vis Sci. 2017 Jun 7; 58(8):2947.

Gupta A, El-Rami H, Barham R, Fleming A, van Hemert J, Sun JK, Silva PS, Aiello LP. Comparison of retinal image sharpness and visible retinal area between two ultrawide field (UWF) cameras. Poster presented at the 2016 ARVO Annual Meeting; May 1, 2016. Seattle, WA. [abstract] Invest Ophth Vis Sci. 2016 Sep 1; 57(12):1645.

Rami HE, Barham R, Gupta A, Fleming A, van Hemert J, Sun JK, Silva PS, Aiello LP. Correlation of hemorrhages and/or microaneurysms (H/Ma) severity and counts between ultrawide field (UWF) retinal imaging and standard ETDRS color stereoscopic retinal photography (ETDRS Photos). Poster presented at the 2016 ARVO Annual Meeting; May 1, 2016. Seattle, WA. [abstract] Invest Ophth Vis Sci. 2016 Sep 1; 57(12):1660.

Haleem MS, Han L, van Hemert J, Fleming A, Pasquale LR, Silva PS, Song BJ, Aiello LP. Regional image features model for automatic classification between normal and glaucoma in fundus and scanning laser ophthalmoscopy (SLO) images. J Med Syst. 2016 Jun 1;40(6):132. doi: 10.1007/s10916-016-0482-9

Haleem MS, Han L, van Hemert J, Fleming A. Glaucoma classification using regional wavelet features of the ONH and its surroundings. Poster presented at the 2015 37th Annual International Conference of the IEEE EMBC; August 25, 2015. Milan, Italy. doi: 10.1109/EMBC18176.2015

Haleem MS, Han L, van Hemert J, Li B, Fleming A. Retinal area detector from scanning laser ophthalmoscope (SLO) images for diagnosing retinal diseases. IEEE J Biomed Health Inform. 2015 Jul 1;19(4):1472-82. doi: 10.1109/JBHI.2014.2352271

Prescott G, Sharp P, Goatman K, Scotland G, Fleming A, Philip S, Staff R, Santiago C, Borooah S, Broadbent D, Chong V, Dodson P, Harding S, Leese G, Megaw R, Styles C, Swa K, Wharton H, Olson J. Improving the cost-effectiveness of photographic screening for diabetic macular oedema: a prospective, multi-centre, UK study. Br J Ophthalmol. 2014 Aug 1;98(8):1042-9. doi: 10.1136/bjophthalmol-2013-304338

Croft DE, van Hemert J, Wykoff CC, Clifton D, Verhoek M, Fleming A, Brown DM. Precise montaging and metric quantification of retinal surface area from ultra-widefield fundus photography and fluorescein angiography. Osli Retina. 2014 Jul 1;45(4):312-7. doi: 10.3928/23258160-20140709-07

Croft D, van Hemert J, Wykoff CC, Clifton D, Verhoek M, Fleming A, Brown DM. Quantification of retinal surface-area from montaged ultra-widefield fundus photography. Poster presented at the 2014 ARVO Annual Meeting; May 4, 2014. Orlando, FL. [abstract] Invest Ophth Vis Sci. 2014 Apr 1; 55(13):4817.

Fleming A, Philip S, Prescott G, Olson J, Sharp P. Presence of retinopathy and a high microaneurysm count increase the risk of subsequent cardiovascular disease. Poster presented at the Diabetes UK professional conference 2014; March 5, 2014. Liverpool, UK. [abstract] Diabet Med. 2014 Mar 1; 31(S1):86-7. doi: 10.1111/dme.12378_2

Haleem MS, Han L, van Hemert J, Li B, Fleming A. Superpixel based retinal area detection in SLO images. Poster presented at the ICCVG 2014 International Conference; September 15, 2014. Warsaw, Poland. [abstract] Computer vision and graphics. 2014; 8671:254-61. doi: 10.1007/978-3-319-11331-9_31

Olson J, Sharp P, Goatman K, Prescott G, Scotland G, Fleming A, Philip S, Santiago C, Borooah S, Broadbent D, Chong V, Dodson P, Harding S, Leese G, Styles C, Swa K, Wharton H. Improving the economic value of photographic screening for optical coherence tomography-detectable macular oedema: a prospective, multicentre, UK study. Health Technol Assess. 2013 Nov 1;17(51):1-142. doi: 10.3310/hta17510

Fleming AD, Philip S, Goatman KA, Sharp PF, Olson JA. Automated clarity assessment of retinal images using regionally based structural and statistical measures. Med Eng Phys. 2012 Sep 1;34(7):849-59. doi: 10.1016/j.medengphy.2011.09.027

Goatman KA, Philip S, Fleming AD, Harvey RD, Swa KK, Styles C, Black M, Sell G, Lee N, Sharp PF, Olson JA. External quality assurance for image grading in the Scottish diabetic retinopathy screening programme. Diabet Med. 2012 Jun 1;29(6):776-83. doi: 10.1111/j.1464-5491.2011.03504.x

Fleming A, Olson JA, Sharp PF, Goatman KA, Philip S. Response to 'Improved automated screening of diabetic retinopathy' by Carlos M. Oliveira et al. Ophthalmologica. 2012 Jan 1;227(3):173. doi: 10.1159/000334922

Lock AD, Allen AR, Fleming AD, Goatman KA. The effect of watermarking on automated assessment of diabetic retinal images. IEEE T Inf Technol B. 2012 Jan 1.

Goatman KA, Fleming AD, Philip S, Williams GJ, Olson JA, Sharp PF. Detection of new vessels on the optic disc using retinal photographs. IEEE T Med Imaging. 2011 Apr 1;30(4):972-9. doi: 10.1109/TMI.2010.2099236.