Arana A, Wentworth CE, Rivero E. Lymphoma among patients with atopic dermatitis treated with topical corticosteroids and/or topical calcineurin inhibitors. Poster presented at the 19th Congress of the European Academy of Dermatology and Venereology; October 6, 2010. Gothenburg, Sweden. [abstract] J Am Acad Dermatol. 2011 Feb; 64(2(1)):AB3. Previously presented at the 26th International Conference on Pharmacoepidemiology.

BACKGROUND: There is a concern that topical use of immunosuppressants in patients with atopic dermatitis (AD) might increase the risk of lymphoma, particularly in children and adolescents. A previous study (covering the period 1995-2005) found no evidence of an increased lymphoma risk in association with use of topical corticosteroids (TCS) or topical calcineurin inhibitors (TCIs) (pimecrolimus cream [PIC] or tacrolimus ointment [TAC]) in patients with AD. The objective of this presentation is to assess the risk of lymphoma among AD patients exposed to TCS and/or TCIs with a specific focus on patients <20 years old.